Mesterolone represent an oral androgen Which is characterized with anti-estrogenic activity. Dissimilar to other oral supplements, this is neither drug hepatotoxicity no 17-alkylated.In medicine Mesterolone is Widely applied for men in treating sexual dysfunction, Which is the result of low level of testosterone. Mesterolone does not have the propriety to increase production of testosterone in the body, it is just used to correct production of natural male androgen.This supplement is preferred by those bodybuilder / athletes who are sensitive to estrogenic side effects of drought and water retention or gyno.There are many reasons that make Mesterolone Widely used by bodybuilders. First of all oral preparation even being it is not toxic on liver. Another positive thing to know about this drug is that it be added Mesterolone normal androgen levels cause libido improvement. This drug is Often used in order to Maintain the sex drive and reduce SHBG in the human body. Because of its high androgenic proprieties in some cases allows to Achieve Mesterolone hardness of muscles and more defined look.The mechanism by Which it has some effectiveness in this regard is from weakly binding to the estrogen receptor without activating it, and to the aromatase enzyme. In the first case, this partially reduces the number of receptor sites available momentarily bind to estrogen, thus reducing estrogenic activity. In the second case, some fractions of aromatase molecules at any given moment are unavailable to bind and convert testosterone Their binding sites being occupied with mesterolone.